DelveInsight’s Metastatic Prostate Cancer Pipeline report depicts a robust space with 80+ active players working to develop ...

In a recent study published by Nature Communications, researchers uncovered a previously unknown method by which androgen-activated androgen receptors (ARs) increase fucosyltransferase 4 (FUT4 ...

RedHill Biopharma Ltd. (NASDAQ: RDHL) ("RedHill" or the "Company"), a specialty biopharmaceutical company, today announced ...

Traditional therapies targeting androgen receptor (AR) signaling have limited efficacy. In a recent study, researchers investigated the potential of azolato-bridged dinuclear platinum ...

One of the other, very obvious changes was the breast cells that appear to show the highest level of estrogen receptor signaling were reduced dramatically in proportion to the androgen-treated breast.

A protein called the androgen receptor normally functions to guide the development of the prostate—signaling the cells to stop growing, act as normal prostate cells and maintain a healthy state.

The combination of cabozantinib and atezolizumab appeared more effective than switching ARPI therapy in patients with mCRPC and extrapelvic soft-tissue metastases.

Their study (“A TBX2-Driven Signaling Switch from Androgen Receptor to Glucocorticoid Receptor Confers Therapeutic Resistance in Prostate Cancer”), which was published in December 2024 by ...

In 2022, there were 2.3 million women diagnosed with breast cancer and 670,000 deaths worldwide, according to the World ...

Activation of the androgen receptor (AR) and AR-driven transcriptional programs is central to the pathophysiology of prostate cancer. Despite successful translational efforts in targeting AR, ...

Adding androgen receptor signaling inhibitors (ARSIs) to standard androgen deprivation therapy (ADT) increases the risks of falls and fractures among men with advanced and metastatic prostate ...