The story behind Rob Lowe turning down playing McDreamy in Grey’s Anatomy

It's hard to picture anyone else taking on the role.

Katherine Heigl remembers “Grey’s Anatomy ”costar Eric Dane in raw post: 'I debated this post for days’

"Here’s to your next great adventure," she wrote of Dane, who died on Thursday at the age of 53, almost a year after he announced his ALS diagnosis.

‘Grey’s Anatomy’ cast reacts to beloved costar’s death at 53

Actor Eric Dane died at age 53 on Thursday, Feb. 19, after a battle with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. After Dane’s family confirmed the news, his “Grey’s Anatomy” costars reacted with heartfelt tributes.

Grey's Anatomy Vet Katherine Heigl Breaks Silence On Eric Dane's Death With Moving Tribute

A beautiful message.

‘Grey's Anatomy' Cast and Crew Pay Tribute to Eric Dane: He "Left an Indelible Mark"

Shonda Rhimes, Kevin McKidd, James Pickens Jr. and more behind the ABC medical drama are honoring the late actor who portrayed plastic surgeon Mark Sloan, aka "McSteamy."