By lowering the media volume, and thus increasing the pericellular oxygen, Tan observed lowered hypoxia signaling and transcriptional rewiring that recapitulated a healthier adipocyte cell model.

Learn about our Editorial Policies. When Wolfrum and his team used single-cell RNA sequencing on mouse fat cells they found that adipocytes came in 10 varieties. These findings expand the limited ...

Obesity is a significant risk factor for various metabolic diseases and, in many cases, causes ectopic fat accumulation (i.e.

Fat cells, illustration. The majority of each adipocyte (fat cell) is filled with a lipid droplet (yellow). Cell nuclei are red. Adipocytes form adipose tissue, which stores energy as an ...