Underscoring the entire schedule is that the 2025 campaign will be the last in their longtime home of Highmark Stadium, where they began playing in 1973. As their new stadium across the street is scheduled to be ready for the 2026 season, the Bills have one final chance to chase Super Bowl glory in their farewell season to their 53-year home.

At some point, it feels like the Bills are finally going to win the Super Bowl, as the franchise has completely turned around under superstar Josh Allen. The reigning MVP tends to light up teams in the regular season,

Yet, once again, the Kansas City Chiefs intervened. Patrick Mahomes’ squad — who have beaten the Bills in the playoffs four times these past five years — dealt a crushing blow and beat Buffalo, 32-29, in the AFC Championship Game.